He told Sky News's Sunday Morning With Trevor Phillips that many in the NHS would agree with his criticisms of the “layers of bureaucracy” and “duplication” between his department and NHS England.
But he added: “They would all agree with that, but will there be a lot of people this weekend who are deeply anxious about their futures? Absolutely. I’m genuinely sorry about that because we don’t want them to be in that position, but I’ve got to make the changes that are necessary.”
The Government has so far declined to say how many jobs it expects to be shed as a result of the abolition of NHS England, which has overseen the administration of the health service across England since 2012.
Further jobs could be lost as Mr Streeting indicated he will look to scrap other health-related quangos, writing in The Sunday Telegraph that axing NHS England is “the beginning, not the end”.
On Sunday, he declined to say which bodies could be in the firing line, saying decisions will follow publication of a review of regulators by incoming NHS England chairwoman Penny Dash.
Speaking to the BBC’s Sunday With Laura Kuenssberg programme, he added: “I'm going after the bureaucracy, not the people who work in it. Of course, I can’t sugar-coat the fact that there will be a significant number of job losses and we will want to make sure we are treating people fairly, supporting them properly through that process. I’m not criticising them,...